1,245 research outputs found
Personal Information Breach as a Service Failure: Examining Relationships among Recovery Efforts, Justice, and Customer Responses
Information service users are required to provide personal information to service providers. Accordingly, Personal Information Breach (PIB) and side-effects have recently emerged. This study will seek answers to the following research questions: (1) In a PIB context, which types of PI are regarded as sensitive, and which recovery efforts are important?, (2) What effects do the company’s recovery efforts have on perceived justice, and how do these relationships vary according to the type of PIB?, and (3) What are the relationships between justice and customers’ responses? This study is significant since it views PIB as a type of service failure, and suggests a research model based on service failure/recovery processes and justice theory, and will empirically be tested. This study aims at strengthening its validity by employing a multi-method approach combining a survey and an experiment. Thus, the research findings will provide theoretical and practical contributions to information privacy areas
Herbal Remedies for Combating Irradiation: a Green Antiirradiation Approach
Plants play important roles in human life not only as suppliers of oxygen but also as a fundamental resource to sustain the human race on this earthly plane. Plants also play a major role in our nutrition by converting energy from the sun during photosynthesis. In addition, plants have been used extensively in traditional medicine since time immemorial. Information in the biomedical literature has indicated that many natural herbs have been investigated for their efficacy against lethal irradiation. Pharmacological studies by various groups of investigators have shown that natural herbs possess significant radioprotective activity. In view of the immense medicinal importance of natural product based radioprotective agents, this review aims at compiling all currently available information on radioprotective agents from medicinal plants and herbs, especially the evaluation methods and mechanisms of action. In this review we particularly emphasize on ethnomedicinal uses, botany, phytochemistry, mechanisms of action and toxicology. We also describe modern techniques for evaluating herbal samples as radioprotective agents. The usage of herbal remedies for combating lethal irradiation is a green antiirradiation approach for the betterment of human beings without high cost, side effects and toxicity
Market Segmentation of Information Systems Academic Programs
Past Information Systems (IS) curriculum studies recognize the importance of the practitioner’s perspective and attempt to incorporate “real world” IS skill requirements within recommended IS model curriculum guidelines. While recent IS curriculum recommendations move towards a greater customer orientation, many practitioners still feel IS education programs are not producing the types of IS professionals needed on their job sites. This raises an important question: Given the significant role that practitioners have played in recommending new curriculum designs, why are IS practitioners not satisfied with the quality and skill training of IS graduates? While many reasons, such as poor curriculum implementation and the rapid change of technology, may contribute to this problem, a significant contributor may be that blanket adoption of national IS model curriculum fails to recognize the basic marketing concept of segmentation. We posit that understanding the customers of IS academic programs in segmented markets should lead to better designed curriculum and accordingly, deliver students that better meet specific market demands. Rather than simply ranking IS employer skill preferences on a national basis, this study relies on the marketing reference discipline for guidance in introducing a market segmentation model and an implementation approach to help bridge the gap between academia and practitioners
Fundamental thickness limit of itinerant ferromagnetic SrRuO thin films
We report on a fundamental thickness limit of the itinerant ferromagnetic
oxide SrRuO that might arise from the orbital-selective quantum confinement
effects. Experimentally, SrRuO films remain metallic even for a thickness
of 2 unit cells (uc), but the Curie temperature, T, starts to decrease at 4
uc and becomes zero at 2 uc. Using the Stoner model, we attributed the T
decrease to a decrease in the density of states (N). Namely, in the thin
film geometry, the hybridized Ru-d orbitals are terminated by top and
bottom interfaces, resulting in quantum confinement and reduction of N.Comment: 20 pages, 4 figure
What Determines Actual Use of Mobile Web Browsing Services? A Contextual Study in Korea
The use of mobile Web browsing services is a worldwide phenomenon. The intent of this research is to produce a testable model of Web browsing services use that both identifies unique national market differences and yet is theoretically parsimonious enough to permit future cross-national studies. Specifically, our model examines which factors determine the use of mobile Web browsing services in South Korea. We show that content quality, hardware quality, ubiquity, cost, and relational factors are important predictors of actual use of mobile Web browsing services. However, counter to our model’s predictions, network quality and security did not appear to be significant factors in Korea at this point of market maturity. Future empirical examination of the proposed model in different markets worldwide should provide multinational IT vendors with better understanding of the similarities and differences in the global smart phone business
NNT pseudoexon activation as a novel mechanism for disease in two siblings with familial glucocorticoid deficiency
CONTEXT:
Intronic DNA frequently encodes potential exonic sequences called pseudoexons. In recent years, mutations resulting in aberrant pseudoexon inclusion have been increasingly recognized to cause disease.
OBJECTIVES:
To find the genetic cause of familial glucocorticoid deficiency (FGD) in two siblings.
PATIENTS:
The proband and his affected sibling, from nonconsanguineous parents of East Asian and South African origin, were diagnosed with FGD at the ages of 21 and 8 months, respectively.
DESIGN:
Whole exome sequencing was performed on genomic DNA (gDNA) of the siblings. Variants in genes known to cause FGD were assessed for causality. Further analysis of gDNA and cDNA was performed by PCR/RT-PCR followed by automated Sanger sequencing.
RESULTS:
Whole exome sequencing identified a single, novel heterozygous variant (p.Arg71*) in nicotinamide nucleotide transhydrogenase (NNT) in both affected individuals. Follow-up cDNA analysis in the proband identified a 69-bp pseudoexon inclusion event, and Sanger sequencing of his gDNA identified a 4-bp duplication responsible for its activation. The variants segregated with the disease: p.Arg71* was inherited from the mother, the pseudoexon change was inherited from the father, and an unaffected sibling had inherited only the p.Arg71* variant.
CONCLUSIONS:
FGD in these siblings is caused by compound heterozygous mutations in NNT; one causing pseudoexon inclusion in combination with another leading to Arg71*. Discovery of this pseudoexon activation mutation highlights the importance of identifying sequence changes in introns by cDNA analysis. The clinical implications of these findings include: facilitation of antenatal genetic diagnosis, early institution of potentially lifesaving therapy, and the possibility of preventative or curative interventio
The Full Range of Predictions for B Physics From Iso-singlet Down Quark Mixing
We extend the range of predictions of the isosinglet (or vector) down quark
model to the fully allowed physical ranges, and also update this with the
effect of new physics constraints. We constrain the present allowed ranges of
sin(2*beta) and sin(2*alpha), gamma, x_s, and A_{B_s}. In models allowing
mixing to a new isosinglet down quark (as in E_6) flavor changing neutral
currents are induced that allow a Z^0 mediated contribution to B-Bbar mixing
and which bring in new phases. In (rho, eta), (x_s, sin(gamma)), and (x_s,
A_{B_s}) plots for the extra isosinglet down quark model which are herein
extended to the full physical range, we find new allowed regions that will
require experiments on sin(gamma) and/or x_s to verify or to rule out an extra
down quark contribution.Comment: 13 pages in RevTeX, 7 postscript figure
The Zwicky Transient Facility: Surveys and Scheduler
We present a novel algorithm for scheduling the observations of time-domain
imaging surveys. Our Integer Linear Programming approach optimizes an observing
plan for an entire night by assigning targets to temporal blocks, enabling
strict control of the number of exposures obtained per field and minimizing
filter changes. A subsequent optimization step minimizes slew times between
each observation. Our optimization metric self-consistently weights
contributions from time-varying airmass, seeing, and sky brightness to maximize
the transient discovery rate. We describe the implementation of this algorithm
on the surveys of the Zwicky Transient Facility and present its on-sky
performance.Comment: Published in PASP Focus Issue on the Zwicky Transient Facility
(https://dx.doi.org/10.1088/1538-3873/ab0c2a). 13 Pages, 11 Figure
Evidence for the Decay Sigma+ -> p mu+ mu-
We report the first evidence for the decay Sigma+ -> p mu+ mu- from data
taken by the HyperCP experiment(E871) at Fermilab. Based on three observed
events, the branching ratio is B(Sigma+ -> p,mu+,mu-) = [8.6 +6.6,-5.4(stat)
+/-5.5(syst)] x 10**-8. The narrow range of dimuon masses may indicate that the
decay proceeds via a neutral intermediate state, Sigma+ -> p P0, P0 -> mu+ mu-,
with a P0 mass of 214.3 +/- 0.5 MeV/c**2 and branching ratio B(Sigma+ -> p P0;
P0 -> mu+ mu-) = [3.1 +2.4,-1.(stat) +/-1.5(syst)] x 10**-8.Comment: As published in PR
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